Fakta om udbudet
Udbyder
University of Copenhagen
Vindere
(18.03.2022)
Metabolon Inc.
617 Davis Drive, Suite 100
NC 27560 Morrisville
Acquisition of a Metabolon analysis
University of Copenhagen
Voluntary ex ante transparency notice
Services
Section I: Contracting authority/entity
Postal address: Nørregade 10
Town: Copenhagen K
NUTS code: DK01 Hovedstaden
Postal code: 1165
Country: Denmark
Contact person: Mahmut Yüksel
E-mail: Fgn253@ku.dk
Internet address(es):
Main address: www.KU.dk
Section II: Object
Acquisition of a Metabolon analysis
Global profiling of metabolites
The aim of the study is to investigate if exercise can improve the metabolism in diabetic patients, and plasma and muscle samples will therefore be collected both immediately and after an acute bout of exercise. Metabolon Inc. has developed an analytical platform that is optimized to detect small metabolite molecules by using stepwise mass spectrometric analyzes followed by analyses with their specially developed software, Metabolyzer ™, setting quantified metabolites into a biological context.
Section IV: Procedure
- The works, supplies or services can be provided only by a particular economic operator for the following reason:
- absence of competition for technical reasons
- New works/services, constituting a repetition of existing works/services and ordered in accordance with the strict conditions stated in the directive
Metabolon Inc. is a leader in high-throughput metabolomics technology, and combines several stepwise liquid chromatography/mass spectrometry (LC/MS) analyses with tailored software, setting the identified metabolites into their biological context.
In order to identify and quantify the metabolites in a sample, a known standard is used as reference, every time a LC/MS analyses is performed in the laboratory. Metabolon Inc. has developed a large in-house metabolite library with chromatograms and mass fragmentation spectra for over 5,200 known chemical standards. Their metabolomics
platform can therefore produce a very high and precise coverage of metabolites in a sample (to Metabolon’s knowledge – based on what is reported in the public domain – no one else has such a large metabolite library).
Once the metabolites have been identified and quantified, the next step is to get a better understanding of their biological role. Metabolon has developed a powerful statistical and analytical software, Metabolyzer™, that is specifically tailored for analyses of post-processed LC/MS based metabolomic datasets. It maps metabolites related to key cellular signaling and metabolic networks, thus providing mechanistic insight into the underlying biology of differentially expressed metabolites.
In summary, we have chosen Metabolon Inc. for this Fee-for Service project, as we believe that their comprehensive metabolite library combined with their curated and elaborate software provides a service that is quite unique.
Section V: Award of contract/concession
Postal address: 617 Davis Drive, Suite 100
Town: Morrisville
NUTS code: US United States
Postal code: NC 27560
Country: United States
Internet address: www.metabolon.com
Section VI: Complementary information
Postal address: Nævnenes hus, toldboden 2
Town: Viborg
Postal code: 8800
Country: Denmark
E-mail: NH@naevneneshus.dk
Internet address: www.KLFU.dk