Fakta om udbudet

EU-nr

2022/S 081-218303

Offentliggjort

26.04.2022

Udbudstype

Udbud med forhandling uden forudgående offentliggørelse

Udbyder

University of Copenhagen

Vindere

(26.04.2022)
Bruker Nordic AB
Torshamnsgatan 44
SE-164 40 Kista

Acquisition of an additional timsTOF Pro 2 system

University of Copenhagen

Voluntary ex ante transparency notice

Supplies

Legal Basis:

Directive 2014/24/EU

Section I: Contracting authority/entity

I.1) Name and addresses

Official name: University of Copenhagen
Postal address: Nørregade 10
Town: Copenhagen K
NUTS code: DK01 Hovedstaden
Postal code: 1165
Country: Denmark
Contact person: Mahmut Yüksel
E-mail: Fgn253@ku.dk
Internet address(es):
Main address: www.KU.dk

I.4) Type of the contracting authority

Body governed by public law

I.5) Main activity

Education

Section II: Object

II.1) Scope of the procurement

II.1.1) Title:

Acquisition of an additional timsTOF Pro 2 system

II.1.2) Main CPV code

38433100 Mass spectrometer

II.1.3) Type of contract

Supplies

II.1.4) Short description:

Proteomics Research Infrastructure (PRI) is a state of-the-art mass spectrometry (MS)-based proteomics facility. Founded on 1 July 2020, the new facility provides coordinated, proprietary client access to forerunner proteomic technology, exceptional technical assistance, and streamlined bioinformatic data analysis for the local research community. PRI is funded by the Novo Nordisk Foundation (NNF) and linked to the NNF Center for Protein Research at the University of Copenhagen.

II.1.6) Information about lots

This contract is divided into lots: no

II.1.7) Total value of the procurement (excluding VAT)

Value excluding VAT: 4 840 580.00 DKK

II.2) Description

II.2.3) Place of performance

NUTS code: DK01 Hovedstaden

II.2.4) Description of the procurement:

The timsTOF Pro 2 system comes with a dual-TIMS (trapped ion

mobility spectrometry) analyzer optimized for high-speed

shotgun proteomics. Its unique geometry allows incoming ions

to be accumulated in parallel in the first section, and for ions to

be released dependent on their mobility from the second

section of the dual-TIMS analyzer. This results in nearly 100%

duty cycle, making this parallel accumulation serial fragmentation technique (PASEF) perfectly suited for nanoflow

LC-MS analysis of enzymatically digested complex protein

Mixtures (Meier et al, Journal of Proteome Research 2015, Meier et al Bioarchive, 2019). The timsTOF Pro system provides a unique technology for the identification of peptides, which is highly relevant for the research performed at our facility. The timsTOF from Bruker is the only instrument in the market which has both TIMS and MS technology allowing the PASEF acquisition method. We are already using this technology in our infrastructure and need to increase the capacities due to a high demand in MS analyses.

II.2.5) Award criteria

II.2.11) Information about options

Options: no

II.2.13) Information about European Union funds

The procurement is related to a project and/or programme financed by European Union funds: no

II.2.14) Additional information

Section IV: Procedure

IV.1) Description

IV.1.1) Type of procedure

Negotiated procedure without prior publication

The works, supplies or services can be provided only by a particular economic operator for the following reason:
- protection of exclusive rights, including intellectual property rights
Additional deliveries by the original supplier ordered under the strict conditions stated in the directive

Explanation:

The timsTOF Pro 2 system comes with the Trapped ion mobility which allows Parallel Accumulation Serial Fragmentation (PASEF) acquisition method to provide extremely high speed and sensitivity to reach new depths in shotgun proteomics. Bruker is the only provider for such instrument. Our collaborator laboratory at MaxPlanck institute for biochemistry, Munich had already tested this technology (Meier et al Bioarchive, 2018). We demonstrated that more than 800,000 fragmentation spectra in standard 120 min LC runs are easily achievable, which can be used for near exhaustive precursor selection in complex mixtures or re-sequencing weak precursors. Online PASEF achieves a remarkable sensitivity with more than 2,900 proteins identified in 30 min runs of only 10ng HeLa digest. This technology is highly relevant for high sample throughput and measurement of low input material samples, which is essential for the projects in our facility.

Patents Covering Unique Features:

- TIMS cell (BIL 031/08), Title: “Apparatus and method for parallel flow ion mobility spectrometry combined with mass spectrometry”

Issued: US7838826B1; US 8288717B2

- Temporal Zoom, IMEX (BDAL 293/11), Title: “Spectrum Acquisition Modes For Ion Mobility Spectrometers Using Trapped Ions”

Issued: US8766176B2; GB2490387B

Pending: DE102012004398A1

- Spatial Zoom (BRE 399/15, BRE 404/15), Title: “Spatial zoom mode for accumulative trapped ion mobility spectrometry”

Issued: US9304106B1; US9546980B1

Pending: EP3054475A1; EP3165913A1; US20170125234A1; CN105869980A; CN107039231A

- Parallel Accumulation TIMS (BRE 398/15), Title: “Trapping ion mobility spectrometer with parallel accumulation”

Issued: US9683964B2

Pending: EP3054473A1; CN105869983A

- Parallel Accumulation - Serial Fragmentation, PASEF (BRE 405/15), Title: “Acquisition of fragment ion mass spectra of ions separated by their mobility”

Pending: EP3165914A1; US20170122906A1; CN107037170A

The intended procurement complements two existing timsTOFpro instruments in our facility. The new systems must be identical to these to ensure internal comparability and alignment with existing systems.

IV.1.3) Information about framework agreement

IV.1.8) Information about the Government Procurement Agreement (GPA)

The procurement is covered by the Government Procurement Agreement: yes

IV.2) Administrative information

Section V: Award of contract/concession

V.2) Award of contract/concession

V.2.1) Date of contract award decision:

28/03/2022

V.2.2) Information about tenders

The contract has been awarded to a group of economic operators: no

V.2.3) Name and address of the contractor/concessionaire

Official name: Bruker Nordic AB
Postal address: Torshamnsgatan 44
Town: Kista
NUTS code: SE Sverige
Postal code: SE-164 40
Country: Sweden
Telephone: +46 086552500

The contractor/concessionaire will be an SME: no

V.2.4) Information on value of the contract/lot/concession (excluding VAT)

Total value of the contract/lot/concession: 4 840 580.00 DKK

V.2.5) Information about subcontracting

Section VI: Complementary information

VI.3) Additional information:

VI.4) Procedures for review

VI.4.1) Review body

Official name: Danish Public Contracts Appeal Board
Postal address: Nævnenes hus, toldboden 2
Town: Viborg
Postal code: 8800
Country: Denmark
E-mail: NH@naevneneshus.dk
Telephone: +45 72405600
Internet address: www.KLFU.dk

VI.5) Date of dispatch of this notice:

21/04/2022