Fakta om udbudet

EU-nr

2023/S 051-151460

Offentliggjort

13.03.2023

Udbudstype

Udbud med forhandling uden forudgående offentliggørelse

Udbyder

University of Copenhagen

Vindere

(13.03.2023)
Metabolon Inc.
617 Davis Drive, Suite 100
NC 27560 Morrisville

Acquisition of a Metabolon analysis

University of Copenhagen

Voluntary ex ante transparency notice

Services

Legal Basis:

Directive 2014/24/EU

Section I: Contracting authority/entity

I.1) Name and addresses

Official name: University of Copenhagen
Postal address: Nørregade 10
Town: Copenhagen K
NUTS code: DK01 Hovedstaden
Postal code: 1165
Country: Denmark
Contact person: Mahmut Yüksel
E-mail: fgn253@ku.dk
Internet address(es):
Main address: www.KU.dk

I.4) Type of the contracting authority

Body governed by public law

I.5) Main activity

Education

Section II: Object

II.1) Scope of the procurement

II.1.1) Title:

Acquisition of a Metabolon analysis

II.1.2) Main CPV code

72314000 Data collection and collation services

II.1.3) Type of contract

Services

II.1.4) Short description:

CBMR – Novo Nordisk Foundation Center for Basic metabolic Research

https://cbmr.ku.dk/

https://cbmr.ku.dk/research/integrative-metabolism-and-environmental-influences/zierath-group/

II.1.6) Information about lots

This contract is divided into lots: no

II.1.7) Total value of the procurement (excluding VAT)

Value excluding VAT: 953 000.00 DKK

II.2) Description

II.2.2) Additional CPV code(s)

38000000 Laboratory, optical and precision equipments (excl. glasses)

II.2.3) Place of performance

NUTS code: DK01 Hovedstaden

II.2.4) Description of the procurement:

Global profiling of metabolites

We have previously shown that there is a time-specific effect of exercise in healthy, lean mice. The aim of our new study is to investigate if mice in an obese and insulin-resistant state have an altered metabolomic response to exercise. Blood samples and samples from four different organs will be collected for global metabolomic analysis. Our new study will build on data sets from our 2019 and 2022 publications in Cell Metabolism, where we used Metabolon Inc. for the metabolomic analyses. It is essential for reproducibility in this project to use the same analytical platform as previously. Metabolon Inc. has developed an analytical platform that is optimized to detect small metabolite molecules by using stepwise mass spectrometric analyzes followed by analyses with their specially developed software, Metabolyzer ™, setting quantified metabolites into a biological context.

II.2.5) Award criteria

II.2.11) Information about options

Options: no

II.2.13) Information about European Union funds

The procurement is related to a project and/or programme financed by European Union funds: no

II.2.14) Additional information

Section IV: Procedure

IV.1) Description

IV.1.1) Type of procedure

Negotiated procedure without prior publication

The works, supplies or services can be provided only by a particular economic operator for the following reason:
- absence of competition for technical reasons
New works/services, constituting a repetition of existing works/services and ordered in accordance with the strict conditions stated in the directive

Explanation:

Metabolon Inc. is a leader in high-throughput metabolomics technology and combines several stepwise liquid chromatography/mass spectrometry (LC/MS) analyses with tailored software, setting the identified metabolites into their biological context.

In order to identify and quantify the metabolites in a sample, a known standard is used as reference, every time a LC/MS analysis is performed in the laboratory. Metabolon Inc. has developed a large in-house metabolite library with chromatograms and mass fragmentation spectra for over 5,400 known chemical standards. Their metabolomics platform can therefore produce a very high and precise coverage of metabolites in a sample (to Metabolon’s knowledge – based on what is reported in the public domain – no one else has such a large metabolite library).

Once the metabolites have been identified and quantified, the next step is to get a better understanding of their biological role. Metabolon has developed a powerful statistical and analytical software, Metabolyzer™, that is specifically tailored for analyses of post-processed LC/MS based metabolomic datasets. It maps metabolites related to key cellular signaling and metabolic networks, thus providing mechanistic insight into the underlying biology of differentially expressed metabolites.

In summary, we have chosen Metabolon Inc. for this Fee-for Service project, as we believe that their comprehensive metabolite library combined with their curated and elaborate software provides a service that is quite unique.

The proposed study will build on our data sets published in Cell Metabolism in 2019 and 2022, respectively. In these studies, Metabolon Inc. was used for the metabolomic sample profiling:

https://www.cell.com/cell-metabolism/fulltext/S1550-4131(19)30183-4?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1550413119301834%3Fshowall%3Dtrue

https://www.cell.com/cell-metabolism/fulltext/S1550-4131(21)00635-5?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1550413121006355%3Fshowall%3Dtrue

IV.1.3) Information about framework agreement

IV.1.8) Information about the Government Procurement Agreement (GPA)

The procurement is covered by the Government Procurement Agreement: yes

IV.2) Administrative information

Section V: Award of contract/concession

V.2) Award of contract/concession

V.2.1) Date of contract award decision:

14/02/2023

V.2.2) Information about tenders

The contract has been awarded to a group of economic operators: no

V.2.3) Name and address of the contractor/concessionaire

Official name: Metabolon Inc.
Postal address: 617 Davis Drive, Suite 100
Town: Morrisville
NUTS code: US United States
Postal code: NC 27560
Country: United States
E-mail: DealDesk@metabolon.com

The contractor/concessionaire will be an SME: yes

V.2.4) Information on value of the contract/lot/concession (excluding VAT)

Total value of the contract/lot/concession: 953 000.00 DKK

V.2.5) Information about subcontracting

Section VI: Complementary information

VI.3) Additional information:

VI.4) Procedures for review

VI.4.1) Review body

Official name: Danish Public Contracts Appeal Board
Postal address: Nævnenes hus, tolboden 2
Town: Viborg
Postal code: 8800
Country: Denmark
E-mail: NH@naevneneshus.dk
Telephone: +45 72405600
Internet address: www.KLFU.dk

VI.5) Date of dispatch of this notice:

08/03/2023