Mass spectrometry systems for proteomics and bioimaging

1.1.

Buyer

Official name : Syddansk Universitet

Email : cap@sdu.dk

Legal type of the buyer : Body governed by public law

Activity of the contracting authority : Education

2.1.

Procedure

Title : Mass spectrometry systems for proteomics and bioimaging

Description : Bruker MS package: Bruker timsTOF Ultra2 (including upgrade timsTOF Ultra2 in 2025) Bruker neofleX MALDI TOF-TOF MS/MS Upgrade of timsTOF Pro2 to next-generation timsTOF HT in 2025 Service agreement for Bruker timsTOF fleX instrument

Procedure identifier : aff2863e-b4cc-4e91-baba-b3b85f709117

Previous notice : 82e57145-44c8-463c-93d2-8afc1d64d0d3-01

Internal identifier : 335832

Type of procedure : Negotiated without prior call for competition

2.1.1.

Purpose

Main nature of the contract : Supplies

Main classification ( cpv ): 38000000 Laboratory, optical and precision equipments (excl. glasses)

2.1.3.

Value

Estimated value excluding VAT : 10 500 000,00 DKK

2.1.4.

General information

Additional information : Negotiated procedure without prior publication

Legal basis :

Directive 2014/24/EU

5.1.

Lot : LOT-0000

Title : Mass spectrometry systems for proteomics and bioimaging

Description : Bruker MS package: Bruker timsTOF Ultra2 (including upgrade timsTOF Ultra2 in 2025) Bruker neofleX MALDI TOF-TOF MS/MS Upgrade of timsTOF Pro2 to next-generation timsTOF HT in 2025 Service agreement for Bruker timsTOF fleX instrument

Internal identifier : 335832

5.1.1.

Purpose

Main nature of the contract : Supplies

Main classification ( cpv ): 38000000 Laboratory, optical and precision equipments (excl. glasses)

5.1.2.

Place of performance

Postal address : Syddansk Universitet

Town : Odense

Postcode : 5230

Country subdivision (NUTS) : Fyn ( DK031 )

Country : Denmark

5.1.6.

General information

Procurement Project not financed with EU Funds.

The procurement is covered by the Government Procurement Agreement (GPA) : yes

Additional information : Bruker timsTOF Ultra2 is an electrospray ionization tandem mass spectrometer (ESI MS/MS) with unique capabilities, including next-generation, high-sensitivity CaptiveSpray Ultra2 ion source, trapped ion mobility separation (TIMS) in combination with hybrid quadrupole-time-of-flight (QTOF) mass analyzers. It allows for detection of low-input samples down to the single cell level.The TIMS module is unique as it enables gas-phase separation of molecule isomers, from modified peptides to intact, modified proteins, with a mass resolution >400, followed by MS/MS based sequencing of the biomolecules.The timsTOF Ultra2 allows for several unique high-sensitivity data acquitision modes based on the exclusive PASEF technology, including diaPASEF, midiaPASEF and prm-PASEF for proteomics applications. Bruker is the only manufacturer of ESI-TIMS-QTOF mass spectrometry systems with PASEF technology.The Bruker timsTOF Ultra2 will be upgraded to upcoming next-generation capabilities during 2025. This will support our research programs in top-down protein analysis and sequencing and in native protein analysis, as it expands the MS/MS capabilities of the instrument.Upgrade of Bruker timsTOF Pro2.The purchase includes an upgrade/exchange of existing timsTOF Pro2 instrument to the next-generation timsTOF HT by October 2025. This will boost our proteomics research program by affording enhanced sensitivity for analysis of small sample amounts from biological specimen, while allowing us to maintain the existing computational data analysis workflows. Changing to another platform would require major resources and time. Bruker neofleX TOF-TOF is a matrix-assisted laser desorption/ionization (MALDI) tandem mass spectrometer (MS/MS). This MALDI TOF-TOF system enables both mass analysis, MS/MS and molecular bioimaging. Top-down sequencing of intact proteins is possible. It also allows for MS imaging (MSI) analysis of biological specimen at 20 um spatial resolution at 20 pixels/sec by accurate rastering a 10kHz pulsing UV laser across the sample stage using IntelliSlides. The software enables generation and representation of bioimages based on spatially resolved mass spectometry data. It is compatible with our existing software platform based on SCiLS Lab, Cardinal and RStudio. Changing to another platform would require major resources and time. These Bruker mass spectrometry systems will advance and expand research in molecular mass spectrometry imaging and in biomolecular mass spectrometry, including proteomics. The new Bruker timsTOF technology and its sensitivity, speed, and dynamic range is crucial for SDU's proteomics research program, especially as we prepare to analyze large biological and clinical sample cohorts (time course analysis, dose-response analysis, cell development/differentiation, biofluids, single cell analysis, etc). The precision required for comprehensive analysis aligns with the imminent challenge of measuring significant sample sets of peptides and proteins, underscoring the necessity for advanced ion mobility spectrometry and bioimaging capabilities. The equipment provides full integration into existing work routines, as it adds on to our existing Bruker timsTOF mass spectrometers, MS imaging sample preparation protocols, and data analysis workflows. A change of supplier will therefore require changes to established protocols and integrated software systems, which would be very resource intensive.

5.1.10.

Award criteria

Criterion :

Type : Price

Description : Price

Weight (percentage, exact) : 100

5.1.12.

Terms of procurement

Information about review deadlines : According to the Act on the Complaints Board for Public Procurement, etc. (the law can be accessed at www.retsinformation.dk), the following deadlines apply for filing a complaint: A complaint regarding not being selected must be submitted to the Complaints Board for Public Procurement within 20 calendar days, cf. section 7(1) of the law, from the day after the notification is sent to the affected applicants regarding who has been selected, provided that the notification is accompanied by a justification for the decision in accordance with section 2(1), no. 1, of the law, and section 171(2) of the Public Procurement Act. In other cases, a complaint regarding procurement, cf. section 7(2) of the law, must be submitted to the Complaints Board for Public Procurement within: 45 calendar days after the contracting authority has published a notice in the Official Journal of the European Union announcing that a contract has been awarded. The deadline is calculated from the day after the notice has been published. 20 calendar days from the day after the contracting authority has communicated its decision, cf. section 185(2) of the Public Procurement Act. No later than at the same time a complaint is submitted to the Complaints Board for Public Procurement, the complainant must inform the contracting authority in writing that a complaint has been submitted to the Complaints Board for Public Procurement and whether the complaint has been filed during the standstill period, cf. section 6(4) of the law. In cases where the complaint is not filed during the standstill period, the complainant must also indicate whether a request is made for the suspensive effect of the complaint, cf. section 12(1) of the law. The email address of the Complaints Board for Public Procurement is listed in section VI.4.1). The Complaints Board for Public Procurement's complaints guide can be found at: www.erhvervsstyrelsen.dk.

5.1.15.

Techniques

Framework agreement : No framework agreement

Information about the dynamic purchasing system : No dynamic purchase system

Electronic auction : no

5.1.16.

Further information, mediation and review

Review organisation : Danish Complaints Board for Public Procurement

Organisation providing more information on the review procedures : Danish Competition and Consumer Authority

TED eSender : Comdia ApS

Value of all contracts awarded in this notice : 10 500 000,00 DKK

Direct award :

Justification for direct award : The contract can be provided only by a particular economic operator because of an absence of competition for technical reasons

Other justification : Public Procurement Act Section 80, litra 3 and 4 - Only one supplier: The mass spectrometry systems for proteomics and bioimaging can only be supplied by Bruker Nordic because it is the only known commercial supplier of a system with these technical specifications. There is an objective and proportionate reason for the establishment of specifications which result in there being only one supplier. The possibility that there are other potential suppliers who could deliver the same has been objectively excluded by market consultations.

6.1.

Result lot ldentifier : LOT-0000

Winner selection status : At least one winner was chosen.

6.1.2.

Information about winners

Winner :

Official name : Bruker Nordic AB

Tender :

Tender identifier : 1

Identifier of lot or group of lots : LOT-0000

Value of the tender : 10 500 000,00 DKK

Contract information:

Identifier of the contract : 1

Title : Mass spectrometry systems for proteomics and bioimaging

Date on which the winner was chosen : 16/09/2024

Date of the conclusion of the contract : 30/09/2024

8.1.

ORG-0001

Official name : Syddansk Universitet

Registration number : 29283958

Postal address : Campusvej 55

Town : Odense M

Postcode : 5230

Country subdivision (NUTS) : Fyn ( DK031 )

Country : Denmark

Contact point : Cindie Arendal Petersen

Email : cap@sdu.dk

Telephone : +45 65509297

Internet address : https://www.sdu.dk/

Roles of this organisation :

Buyer

8.1.

ORG-0002

Official name : Bruker Nordic AB

Registration number : SE556577236401

Postal address : Torshamnsgatan 44

Town : Kista

Postcode : SE-16440

Country : Sweden

Email : willy.bjorklund@bruker.com

Telephone : +46 86552500

Roles of this organisation :

Tenderer

Winner of these lots : LOT-0000

8.1.

ORG-1000

Official name : Comdia ApS

Registration number : 33501404

Postal address : Lindvedvej 73

Town : Odense S

Postcode : 5260

Country subdivision (NUTS) : Fyn ( DK031 )

Country : Denmark

Email : support@comdia.com

Telephone : +45 7199 3672

Internet address : https://www.comdia.com/

Roles of this organisation :

TED eSender

8.1.

ORG-1001

Official name : Danish Complaints Board for Public Procurement

Registration number : 37795526

Postal address : Nævnenes Hus, Toldboden 2

Town : Viborg

Postcode : 8800

Country subdivision (NUTS) : Vestjylland ( DK041 )

Country : Denmark

Email : klfu@naevneneshus.dk

Telephone : +45 7240 5600

Internet address : http://www.klfu.dk

Roles of this organisation :

Review organisation

8.1.

ORG-1002

Official name : Danish Competition and Consumer Authority

Registration number : 10294819

Postal address : Carl Jacobsens Vej 35

Town : Valby

Postcode : 2500

Country subdivision (NUTS) : Københavns omegn ( DK012 )

Country : Denmark

Email : kfst@kfst.dk

Telephone : +45 4171 5000

Internet address : https://www.kfst.dk/

Roles of this organisation :

Organisation providing more information on the review procedures

11.1.

Notice information

Notice identifier/version : 8ad468b9-f508-4a60-b0a4-893a50d29bfb - 01

Form type : Result

Notice type : Contract or concession award notice – standard regime

Notice subtype : 29

Notice dispatch date : 02/10/2024 09:01:08 (UTC+2)

Languages in which this notice is officially available : English

11.2.

Publication information

Notice publication number : 595906-2024

OJ S issue number : 193/2024

Publication date : 03/10/2024

Fakta om udbudet

Mass spectrometry systems for proteomics and bioimaging

Syddansk Universitet