Mass spectrometry based equipment for proteomics analyses

1.1.

Buyer

Official name : Danmarks Tekniske Universitet - DTU

Email : mihaiv@dtu.dk

Legal type of the buyer : Body governed by public law

Activity of the contracting authority : Education

2.1.

Procedure

Title : Mass spectrometry based equipment for proteomics analyses

Description : DTU Biosustain is now looking into purchasing equipment for proteomics analyses. The analytics department at DTU Biosustain is providing routine and research-based protemics services to the entire center by means of liquid chromatography-mass spectrometry (which is considered the gold standard technique for such analyses). Proteomics is a tool used by most research groups at DTU Biosustain, and thus, it is considered a fundamental service, which is of high priori-ty to the center. Based on this, DTU Biosustain now wishes to purchase a new equipment to be able to reliably continue the proteomics analyses and to provide the center with the data, which is needed for the research to be performed. The new equipment must be able to: • Perform high-quality proteomics analyses utilizing a built-in option for sample preparation and including the software needed for complex proteomics data processing. • Synchronize the quadrupole with the ion mobility (IMS) elution time to allow for a high MS/MS acquisition speed, leading to an increased fragmentation depth. In addition, the system must include algorithms for intelligent targeting of low-level precursors, as this will enable a very high data coverage also from complex digested protein mixtures • Show a reproducibility of Collisional Cross Section (CCS) value determination <0.5 %RSD, as this will ensure high data reproducibility • Provide pre-defined methods for DDA, DIA and PRM where both m/z and ion mobility are used for selectivity, as well as dual-TIMS technology allowing for PASEF, dia-PASEF and prm-PASEF acquisition methods. These features provide a nearly 100% duty cycle, which is perfectly suited for the nanoflow LC-MS analysis of enzymatically digested protein mix-tures usually analysed within the analytics department at DTU Biosustain. • Allow for the integration of various LC vendors into the instrument control software, as the analytics department at DTU Biosustain has LC systems from different vendors available for these analyses.

Procedure identifier : a6ad59fb-8e2e-4de7-9982-ac0a294bf14d

Previous notice : 55052441-aa2b-45e8-b5f8-e5490261b016-01

Internal identifier : 9649

Type of procedure : Negotiated without prior call for competition

Main features of the procedure : Proteomics analyses are complex and puts a lot of requirements both on the equipment hardware, for analysing the samples, as well as on the software needed to process the complex data produced by the hardware. Currently, only the timsTOF Pro 2 System with an Evosep One LC from Bruker Nordic AB provides all of the abovementioned features as well as an integrated software and hardware service with the capabilities for non-targeted and targeted proteomics. Thus, the equipment can only be supplied by one particular economic operator due to lack of competition for technical reasons cf. the public procurement act section 80 (3) (2). Adding the equipment from Bruker Nordic AB to the existing equipment park in the analytics department at DTU Biosustain will provide the center with the opportunity to have a complementary technique in the laboratory with unique features, which no other supplier can provide. This complementary technique with its unique features is crucial for the research performed at DTU Biosustain, and it will also ensure a constant flow of high-quality data.

2.1.1.

Purpose

Main nature of the contract : Supplies

Main classification ( cpv ): 38000000 Laboratory, optical and precision equipments (excl. glasses)

2.1.2.

Place of performance

Country subdivision (NUTS) : Københavns omegn ( DK012 )

Country : Denmark

2.1.3.

Value

Estimated value excluding VAT : 4 725 950,00 DKK

2.1.4.

General information

Call for competition is terminated

Legal basis :

Directive 2014/24/EU

Danish Public Procurement Act (Udbudsloven) - Danish Public Procurement Act (Act no. 1564 af 15 December 2015 with later changes), implementing directive 2014/24/EU.

5.1.

Lot : LOT-0000

Title : Mass spectrometry based equipment for proteomics analyses

Description : DTU Biosustain is now looking into purchasing equipment for proteomics analyses. The analytics department at DTU Biosustain is providing routine and research-based protemics services to the entire center by means of liquid chromatography-mass spectrometry (which is considered the gold standard technique for such analyses). Proteomics is a tool used by most research groups at DTU Biosustain, and thus, it is considered a fundamental service, which is of high priori-ty to the center. Based on this, DTU Biosustain now wishes to purchase a new equipment to be able to reliably continue the proteomics analyses and to provide the center with the data, which is needed for the research to be performed. The new equipment must be able to: • Perform high-quality proteomics analyses utilizing a built-in option for sample preparation and including the software needed for complex proteomics data processing. • Synchronize the quadrupole with the ion mobility (IMS) elution time to allow for a high MS/MS acquisition speed, leading to an increased fragmentation depth. In addition, the system must include algorithms for intelligent targeting of low-level precursors, as this will enable a very high data coverage also from complex digested protein mixtures • Show a reproducibility of Collisional Cross Section (CCS) value determination <0.5 %RSD, as this will ensure high data reproducibility • Provide pre-defined methods for DDA, DIA and PRM where both m/z and ion mobility are used for selectivity, as well as dual-TIMS technology allowing for PASEF, dia-PASEF and prm-PASEF acquisition methods. These features provide a nearly 100% duty cycle, which is perfectly suited for the nanoflow LC-MS analysis of enzymatically digested protein mix-tures usually analysed within the analytics department at DTU Biosustain. • Allow for the integration of various LC vendors into the instrument control software, as the analytics department at DTU Biosustain has LC systems from different vendors available for these analyses.

Internal identifier : 9649

5.1.1.

Purpose

Main nature of the contract : Supplies

Main classification ( cpv ): 38000000 Laboratory, optical and precision equipments (excl. glasses)

5.1.2.

Place of performance

Country subdivision (NUTS) : Københavns omegn ( DK012 )

Country : Denmark

5.1.3.

Estimated duration

Duration : 1 Year

5.1.5.

Value

Estimated value excluding VAT : 4 725 950,00 DKK

5.1.6.

General information

Procurement Project not financed with EU Funds.

The procurement is covered by the Government Procurement Agreement (GPA) : yes

5.1.10.

Award criteria

Criterion :

Type : Price

Name : Price

Description : Price

Weight (percentage, exact) : 100

5.1.12.

Terms of procurement

Information about review deadlines : Complaint that the Contracting Authority, contrary to the Public Procurement Act, has concluded a contract without prior publication of a contract notice in the European Union Official Journal must be submitted no later than 30 calendar days from the date after a contract award notice has been published by the Contracting Authority in the European Union Official Journal and that contract award notice includes the grounds for the decision to award the contract directly, cf. lov om Klagenævnet for Udbud (Complaints Board for Tenders) § 7, section 3.

5.1.15.

Techniques

Framework agreement : No framework agreement

Information about the dynamic purchasing system : No dynamic purchase system

Electronic auction : no

5.1.16.

Further information, mediation and review

Review organisation : Klagenævnet for Udbud

Organisation providing more information on the review procedures : Konkurrence- og Forbrugerstyrelsen

Organisation signing the contract : Danmarks Tekniske Universitet - DTU

TED eSender : Mercell Holding ASA

Value of all contracts awarded in this notice : 4 725 950,00 DKK

Direct award :

Justification for direct award : The contract can be provided only by a particular economic operator because of an absence of competition for technical reasons

Other justification : Proteomics analyses are complex and puts a lot of requirements both on the equipment hardware, for analysing the samples, as well as on the software needed to process the complex data produced by the hardware. Currently, only the timsTOF Pro 2 System with an Evosep One LC from Bruker Nordic AB provides all of the abovementioned features as well as an integrated software and hardware service with the capabilities for non-targeted and targeted proteomics. Thus, the equipment can only be supplied by one particular economic operator due to lack of competition for technical reasons cf. the public procurement act section 80 (3). Adding the equipment from Bruker Nordic AB to the existing equipment park in the analytics department at DTU Biosustain will provide the center with the opportunity to have a complementary technique in the laboratory with unique features, which no other supplier can provide. This complementary technique with its unique features is crucial for the research performed at DTU Biosustain, and it will also ensure a constant flow of high-quality data.

6.1.

Result lot ldentifier : LOT-0000

Winner selection status : At least one winner was chosen.

6.1.2.

Information about winners

Winner :

Official name : Bruker Nordic AB

Tender :

Tender identifier : Tilbud

Identifier of lot or group of lots : LOT-0000

Value of the tender : 4 725 950,00 DKK

Concession value:

Subcontracting : Not yet known

Contract information:

Identifier of the contract : Tilbud

Date on which the winner was chosen : 16/01/2025

Date of the conclusion of the contract : 10/02/2025

Organisation signing the contract : Danmarks Tekniske Universitet - DTU

6.1.4.

Statistical information :

Received tenders or requests to participate :

Type of received submissions : Tenders from micro, small or medium tenderers

Number of tenders or requests to participate received : 1

Type of received submissions : Tenders from tenderers registered in other European Economic Area countries than the country of the buyer

Number of tenders or requests to participate received : 1

Type of received submissions : Tenders submitted electronically

Number of tenders or requests to participate received : 1

8.1.

ORG-0001

Official name : Danmarks Tekniske Universitet - DTU

Registration number : 30060946

Postal address : Anker Engelunds Vej 1

Town : Kgs. Lyngby

Postcode : 2800

Country subdivision (NUTS) : Københavns omegn ( DK012 )

Country : Denmark

Contact point : Mia Iversen

Email : mihaiv@dtu.dk

Telephone : +45 61262786

Internet address : https://www.dtu.dk

Buyer profile : https://eu.eu-supply.com/ctm/company/companyinformation/index/165863

Roles of this organisation :

Buyer

Organisation signing the contract

8.1.

ORG-0002

Official name : Klagenævnet for Udbud

Registration number : 37795526

Postal address : Nævnenes hus, Toldboden 2

Town : Viborg

Postcode : 8800

Country subdivision (NUTS) : Østjylland ( DK042 )

Country : Denmark

Email : klfu@erst.dk

Telephone : +45 35291000

Internet address : http://www.klfu.dk

Roles of this organisation :

Review organisation

8.1.

ORG-0003

Official name : Konkurrence- og Forbrugerstyrelsen

Registration number : 10294819

Postal address : Carl Jacobsens Vej 35

Town : Valby

Postcode : 2500

Country subdivision (NUTS) : Byen København ( DK011 )

Country : Denmark

Email : kfst@kfst.dk

Telephone : +45 41715000

Internet address : http://www.kfst.dk

Roles of this organisation :

Organisation providing more information on the review procedures

8.1.

ORG-0004

Official name : Bruker Nordic AB

Size of the economic operator : Micro, small, or medium

Registration number : SE556577236401

Postal address : Torshamnsgatan 44

Town : Kista

Postcode : 164 40

Country subdivision (NUTS) : Stockholms län ( SE110 )

Country : Sweden

Email : willy.bjorklund@bruker.com

Telephone : +46 (0)8 655 2500

Roles of this organisation :

Tenderer

Winner of these lots : LOT-0000

8.1.

ORG-0005

Official name : Mercell Holding ASA

Registration number : 980921565

Postal address : Askekroken 11

Town : Oslo

Postcode : 0277

Country subdivision (NUTS) : Oslo ( NO081 )

Country : Norway

Contact point : eSender

Email : publication@mercell.com

Telephone : +47 21018800

Fax : +47 21018801

Internet address : http://mercell.com/

Roles of this organisation :

TED eSender

11.1.

Notice information

Notice identifier/version : 958a3727-38ac-4732-9b52-04625ac38f22 - 01

Form type : Result

Notice type : Contract or concession award notice – standard regime

Notice subtype : 29

Notice dispatch date : 17/02/2025 12:25:13 (UTC)

Notice dispatch date (eSender) : 17/02/2025 13:00:39 (UTC)

Languages in which this notice is officially available : English

11.2.

Publication information

Notice publication number : 108336-2025

OJ S issue number : 34/2025

Publication date : 18/02/2025

Fakta om udbudet

Mass spectrometry based equipment for proteomics analyses

Danmarks Tekniske Universitet - DTU