Fakta om udbudet
Udbyder
Aarhus Universitet
Vindere
(26.05.2017)
Advion Inc.
Bregstavagen 4
S-755 98 Uppsala
Purchase of an integrated TLC-MS System
Aarhus Universitet
Voluntary ex ante transparency notice
Supplies
Section I: Contracting authority/entity
311 19 103
Trøjborgvej 82-84
Aarhus c
8000
Denmark
Contact person: Camilla Ladekarl Sørensen
Telephone: +45 51335271
E-mail: udbud@au.dk
NUTS code: DK
Internet address(es):
Main address: www.au.dk
Section II: Object
Purchase of an integrated TLC-MS System.
In the research group of Prof. Karl Anker Jørgensen, novel methodologies within the fields of asymmetric organocatalysis and dual catalysis are developed. The aim is to access important molecular frameworks in an efficient, stereoselective and environmentally viable fashion through the development and understanding of new catalytic systems. Among others, the perspectives of this research are of high interest to the pharmaceutical and agrochemical industries.
In the research group of Prof. Karl Anker Jørgensen, novel methodologies within the fields of asymmetric organocatalysis and dual catalysis are developed. The aim is to access important molecular frameworks in an efficient, stereoselective and environmentally viable fashion through the development and understanding of new catalytic systems. Among others, the perspectives of this research are of high interest to the pharmaceutical and agrochemical industries.
Issues and needs.
To optimize our workflow, our research group is in need of an analytical tool to aid in directing flash column chromatography, which is the most time-consuming daily operation for most of our researchers. The equipment should also help alleviate queue problems on our NMR-apparatus, which is highly necessary to avoid the current bottle-neck situation.
— An integrated TLC-MS system will allow for directed column chromatography of complex reaction mixtures based on TLC-analysis.
— An MS system with no sample preparation allowing for swift analysis of reaction mixtures and fractions from column chromatography will significantly lower the pressure on our NMR-apparatus.
— Integrated software to control both TLC-MS analysis and direct MS analysis.
— Package solution to be setup by supplier as soon as possible and sufficient training of group members must be provided as none of us are experts on MS-systems.
— The possibility to attach HPLC and UPC2 with chiral stationary phase columns that we already possess must exist.
— Two ionization sources with both positive and negative modes to ensure broad applicability.
— Additional equipment should be available to analyze air sensitive compounds as our research in the future is likely to involve sensitive catalytic transition metal species.
— The equipment must be relatively compact because of limited space.
Market analysis.
Two TLC-MS interfaces that are commercially available could be considered (other equipment including TLC-DESI-MS, TLC-DART-MS and TLC-MALDI-MS are either not commercial or suitable for small molecule analysis).
— The TLC-MS apparatus by CAMAG is a TLC-MS interface sold separately, and has to be attached to an existing LC-MS.
— Plate Express™ TLC-MS Interface by Advion is an integrated TLC-MS system sold in conjunction with an expression compact mass spectrometer (CMS).
Conclusion.
Only Advion can provide a fully integrated TLC-MS system (Expression CMS with Plate Express TLC-MS interface and ASAP probe) that also meets our requirements for the mass spectrometry apparatus, software etc. as listed above.
Section IV: Procedure
- The procurement falls outside the scope of application of the directive
To optimize our workflow, our research group is in need of an analytical tool to aid in directing flash column chromatography, which is the most time-consuming daily operation for most of our researchers. The equipment should also help alleviate queue problems on our NMR-apparatus, which is highly necessary to avoid the current bottle-neck situation.
— An integrated TLC-MS system will allow for directed column chromatography of complex reaction mixtures based on TLC-analysis.
— An MS system with no sample preparation allowing for swift analysis of reaction mixtures and fractions from column chromatography will significantly lower the pressure on our NMR-apparatus.
— Integrated software to control both TLC-MS analysis and direct MS analysis.
— Package solution to be setup by supplier as soon as possible and sufficient training of group members must be provided as none of us are experts on MS-systems.
— The possibility to attach HPLC and UPC2 with chiral stationary phase columns that we already possess must exist.
— Two ionization sources with both positive and negative modes to ensure broad applicability.
— Additional equipment should be available to analyze air sensitive compounds as our research in the future is likely to involve sensitive catalytic transition metal species.
— The equipment must be relatively compact because of limited space.
Market analysis.
Two TLC-MS interfaces that are commercially available could be considered (other equipment including TLC-DESI-MS, TLC-DART-MS and TLC-MALDI-MS are either not commercial or suitable for small molecule analysis).
— The TLC-MS apparatus by CAMAG is a TLC-MS interface sold separately, and has to be attached to an existing LC-MS.
— Plate Express™ TLC-MS Interface by Advion is an integrated TLC-MS system sold in conjunction with an expression compact mass spectrometer (CMS).
Only Advion can provide a fully integrated TLC-MS system (Expression CMS with Plate Express TLC-MS interface and ASAP probe) that also meets our requirements for the mass spectrometry apparatus, software etc. as listed above.
Section V: Award of contract/concession
Bregstavagen 4
Uppsala
S-755 98
Sweden
Telephone: +46 703108410
NUTS code: SE
Section VI: Complementary information
Dahlerups Pakhus — Langelinie Allé 17
København Ø
2100
Denmark
Telephone: +45 35291000
E-mail: klfu@erst.dk
Carl Jacobsens Vej 35
Valby
2500
Denmark
Telephone: +45 4171500
E-mail: kfst@kfst.dk
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