23948sdkhjf
Log ind eller opret et abonnement for at gemme artikler
Få adgang til alt indhold på Electronic Supply
Annonce
Annonce

Fakta om udbudet

EU-nr
Offentliggjort
04.09.2025
Udbudstype
Andre

Udbyder

Aalborg Universitet

Procurement of spectrofluorometer


Aalborg Universitet

578331-2025 - Competition
Denmark – Spectrometers – Procurement of spectrofluorometer
OJ S 169/2025 04/09/2025
Contract or concession notice – standard regime
Supplies - Services
1. Buyer
1.1.
Buyer
Official name Aalborg Universitet
Email ahra@adm.aau.dk
Legal type of the buyer Organisation awarding a contract subsidised by a central government authority
Activity of the contracting authority Education
2. Procedure
2.1.
Procedure
Title Procurement of spectrofluorometer
Description Mutations in the archetypal Ca2+-sensor calmodulin (CaM) are associated with life-threat-ening cardiac arrhythmias in children. Yet, population wide sequencing studies now reveal carriers of CaM mutations who are seemingly healthy. This extreme segregation of phenotypes warrants a deeper understanding of the molecular impact of CaM mutations, to understand why some variants result in a pathogenic phenotype and other variants do not. Thus, the aim of this project is to determine which human Calmodulin mutations impair the ability to bind Ca2+-ions and decode intracellular Ca2+-signals to target proteins. We wish to upgrade our experimental platform with a new spectrofluorometer for measuring the Ca2+-affinity of CaM variants. Calcium binding to the CaM N- and C-lobe can be followed by intrinsic Phe and Tyr fluorescence, respectively. The change in fluorescence signal upon Ca2+-binding is small and demands high sensitivity and spectral specificity to be accurately and reliably measured. The optical configuration of the spectrofluorometer we seek needs to meet these requirements. The instrument should further be equipped with a fluorescence anisotropy module to enable characterization of CaM binding to TAMRA-labeled CaM-binding domains from target proteins.
Procedure identifier 22a9f2bd-196d-4bc0-a884-0659adc71e26
Internal identifier 29317dc1-931a-4f11-b23c-c77ba14059b8
Type of procedure Other single stage procedure
2.1.1.
Purpose
Main nature of the contract Supplies
Additional nature of the contract Services
Main classification   ( cpv ):  38433000   Spectrometers
2.1.2.
Place of performance
Country subdivision (NUTS) Nordjylland   ( DK050 )
Country Denmark
2.1.4.
General information
Legal basis
Directive 2014/24/EU
2.1.6.
Grounds for exclusion
Sources of grounds for exclusion Procurement Document
5. Lot
5.1.
Lot LOT-0000
Title Procurement of spectrofluorometer
Description Mutations in the archetypal Ca2+-sensor calmodulin (CaM) are associated with life-threat-ening cardiac arrhythmias in children. Yet, population wide sequencing studies now reveal carriers of CaM mutations who are seemingly healthy. This extreme segregation of phenotypes warrants a deeper understanding of the molecular impact of CaM mutations, to understand why some variants result in a pathogenic phenotype and other variants do not. Thus, the aim of this project is to determine which human Calmodulin mutations impair the ability to bind Ca2+-ions and decode intracellular Ca2+-signals to target proteins. We wish to upgrade our experimental platform with a new spectrofluorometer for measuring the Ca2+-affinity of CaM variants. Calcium binding to the CaM N- and C-lobe can be followed by intrinsic Phe and Tyr fluorescence, respectively. The change in fluorescence signal upon Ca2+-binding is small and demands high sensitivity and spectral specificity to be accurately and reliably measured. The optical configuration of the spectrofluorometer we seek needs to meet these requirements. The instrument should further be equipped with a fluorescence anisotropy module to enable characterization of CaM binding to TAMRA-labeled CaM-binding domains from target proteins.
Internal identifier 3119c93d-9fbf-403d-b7ec-39ab71098a05
5.1.1.
Purpose
Main nature of the contract Supplies
Additional nature of the contract Services
Main classification   ( cpv ):  38433000   Spectrometers
5.1.2.
Place of performance
Country subdivision (NUTS) Nordjylland  ( DK050 )
Country Denmark
5.1.3.
Estimated duration
Start date 15/10/2025
Duration end date 15/12/2025
5.1.6.
General information
Reserved participation Participation is not reserved.
Procurement Project not financed with EU Funds.
The procurement is covered by the Government Procurement Agreement (GPA) yes
5.1.9.
Selection criteria
Sources of selection criteria Procurement Document
5.1.11.
Procurement documents
5.1.12.
Terms of procurement
Terms of submission
Electronic submission Required
Languages in which tenders or requests to participate may be submitted English
Electronic catalogue Not allowed
Deadline for receipt of tenders 22/09/2025   22:00:00 (UTC) Western European Time, GMT
Terms of contract
The execution of the contract must be performed within the framework of sheltered employment programmes No
Electronic invoicing Required
Electronic ordering will be used yes
Electronic payment will be used yes
5.1.15.
Techniques
Framework agreement
No framework agreement
Information about the dynamic purchasing system
No dynamic purchase system
Electronic auction no
5.1.16.
Further information, mediation and review
Review organisation Klagenævnet for Udbud
Organisation providing more information on the review procedures Konkurrence- og Forbrugerstyrelsen
8. Organisations
8.1.
ORG-0001
Official name Aalborg Universitet
Registration number 29102384
Postal address Fredrik Bajers Vej 7K
Town Aalborg Øst
Postcode 9220
Country subdivision (NUTS) Nordjylland  ( DK050 )
Country Denmark
Contact point Alexander Herskind Rasmussen
Email ahra@adm.aau.dk
Telephone 22505186
Roles of this organisation
Buyer
8.1.
ORG-0002
Official name Klagenævnet for Udbud
Registration number 37795526
Postal address Toldboden 2
Town Viborg
Postcode 8800
Country subdivision (NUTS) Vestjylland  ( DK041 )
Country Denmark
Contact point Klagenævnet for Udbud
Telephone +45 72405600
Information exchange endpoint (URL) https://naevneneshus.dk/start-din-klage/klagenaevnet-for-udbud/
Roles of this organisation
Review organisation
8.1.
ORG-0003
Official name Konkurrence- og Forbrugerstyrelsen
Registration number 10294819
Postal address Carl Jacobsens Vej 35
Town Valby
Postcode 2500
Country subdivision (NUTS) Byen København  ( DK011 )
Country Denmark
Contact point Konkurrence- og Forbrugerstyrelsen
Email kfst@kfst.dk
Telephone +45 41715000
Information exchange endpoint (URL) https://www.kfst.dk
Roles of this organisation
Organisation providing more information on the review procedures
8.1.
ORG-0004
Official name Mercell Holding ASA
Registration number 980921565
Postal address Askekroken 11
Town Oslo
Postcode 0277
Country subdivision (NUTS) Oslo  ( NO081 )
Country Norway
Contact point eSender
Telephone +47 21018800
Fax +47 21018801
Internet address http://mercell.com/
Roles of this organisation
TED eSender
Notice information
Notice identifier/version 078b6cd5-4089-4829-b717-059afe97c273   -   01
Form type Competition
Notice type Contract or concession notice – standard regime
Notice subtype 16
Notice dispatch date 03/09/2025   11:51:08 (UTC) Western European Time, GMT
Notice dispatch date (eSender) 03/09/2025   12:05:20 (UTC) Western European Time, GMT
Languages in which this notice is officially available English
Notice publication number 578331-2025
OJ S issue number 169/2025
Publication date 04/09/2025
Annonce Annonce
BREAKING
{{ article.headline }}
0.032|