Low-flow liquid chromatography ultrahigh-resolution mass spectrometry platform

1.1.

Buyer

Official name : Danmarks Tekniske Universitet - DTU

Email : kafre@dtu.dk

Legal type of the buyer : Body governed by public law

Activity of the contracting authority : Education

2.1.

Procedure

Title : Low-flow liquid chromatography ultrahigh-resolution mass spectrometry platform

Description : DTU Sustain is working with environmental forensics and metabolomic investigations to study the fate and occurrence of chemicals and small molecules dispersed into the environment. To be able to make these investigations, DTU wants to procure a low-flow liquid chromatography ultrahigh-resolution mass spectrometry platform, capable of characterizing small molecules with collisional dissociation and laser-based ultraviolet-photodissociation (UVPD) for multi-stage molecular fragmentation (MSn) in liquid chromatography time scale. The mass spectrometer platform must have two independent mass detectors, and capable of resolving very complex molecular mixtures to improve unknown chemical characterization with fine isotope detection at one million in mass resolution (at mass-to-charge 200) or higher. The liquid chromatography system must be able to make chromatographic separations of complex mixtures at low-flow conditions (10-100 nano-liters per minute) and seamlessly integrated with nanoelectrospray ionization and controlled, jointly with themass spectrometer, within the same software environment. In addition, the combined system must have; • Two atmospheric pressure ionisation interfaces; heated electrospray ionisation (HESI) and nano-spray ionisation (NSI). • A nanoflow UHPLC (ultra-high performance liquid chromatography) instrument that can be operated with the ultrahigh-resolution mass spectrometer, and the combined UHPLCHRMS system is operated within the same software environment. • A nanoflow UHPLC instrument capable of operating from 1 nanoliter per minute to 100 microliter per minute in flow rate, and at backpressures up to 1500 bar. • A nanoflow UHPLC instrument that consist of a binary high-pressure gradient pump, splitloop autosampler, an active nanoflow control unit and onboard user interface for immediate operation. • A UHPLC instrument capable of maintaining sample temperature control within 4-40 oC and holding at least 216 sample vials at the same time. • The UHPLC sampler must support a sample capacity of four sample racks and well plates (96 and 384, deep and shallow) without the need for external devices such as plate feeder. • The user interface must provide guided workflow exchange and maintenance procedures. • The mass spectrometer (MS) must be capable of operating at one million or higher in mass resolution at mass-to-charge (m/z) 200 to resolve complex environmental matrices. • A mass spectrometer capable of performing higher-energy collisional dissiciation and ultraviolet photodissociation for multi-stage MSn-fragmentation in liquid chromatography time scale. • A mass spectrometer capable of fragment ion detection in either ion trap or high-resolution analyzer • A mass spectrometer capable of isolating precursor ions with a quadrupole filter with 0.7 FWHM resolution for 50<m/z<1000. • A mass spectrometer that can perform automated iterative data-dependent acquisition in an integrated software solution. • A mass spectrometer that can perform data-dependent acquisition and data-independent acquisition. • A mass spectrometer with three mass analyzers build on quadrupole, linear ion trap, and Orbitrap technology. • A mass spectrometer with two independent mass detectors - one of them based linear ion trap technology - and both detectors must be capable of operating in parallel with each other. • A mass spectrometer with a removable ion sweep cone. • The mass spectrometer must be capable of switching polarities within 25 mili seconds • The mass spectrometer must be able to perform up to 10 stages of data-dependent fragmentations (MSn). • A mass spectrometer with normalized collision energy capability to automatically compensate for the mass dependent energy deposition and provide instrument-to-instrument fragmentation reproducibility. • A mass spectrometer with a data-dependent decision tree logic to automatic determine optimal fragmentation technique and analyzer during the LC run. • The high resolution mass analyzer must at least have an intra-spectrum dynamic range of 5000. • An ultraviolet photodissociation technology using a 213 nm laser architecture that is fully integrated in the mass spectrometer.

Procedure identifier : e2d1bb17-3137-4d25-92c3-9b27224484af

Internal identifier : 10694

Type of procedure : Negotiated without prior call for competition

2.1.1.

Purpose

Main nature of the contract : Supplies

Main classification ( cpv ): 38433100 Mass spectrometer

Additional classification ( cpv ): 38000000 Laboratory, optical and precision equipments (excl. glasses), 38400000 Instruments for checking physical characteristics, 38430000 Detection and analysis apparatus, 38433000 Spectrometers

2.1.2.

Place of performance

Postal address : Miljøvej, building 113

Town : Kgs. Lyngby

Postcode : 2800

Country subdivision (NUTS) : Københavns omegn ( DK012 )

Country : Denmark

2.1.4.

General information

Legal basis :

Directive 2014/24/EU

The Danish Public Procurement Law - The Danish Public Procurement Law

5.1.

Lot : LOT-0000

Title : Low-flow liquid chromatography ultrahigh-resolution mass spectrometry platform

Description : DTU Sustain is working with environmental forensics and metabolomic investigations to study the fate and occurrence of chemicals and small molecules dispersed into the environment. To be able to make these investigations, DTU wants to procure a low-flow liquid chromatography ultrahigh-resolution mass spectrometry platform, capable of characterizing small molecules with collisional dissociation and laser-based ultraviolet-photodissociation (UVPD) for multi-stage molecular fragmentation (MSn) in liquid chromatography time scale. The mass spectrometer platform must have two independent mass detectors, and capable of resolving very complex molecular mixtures to improve unknown chemical characterization with fine isotope detection at one million in mass resolution (at mass-to-charge 200) or higher. The liquid chromatography system must be able to make chromatographic separations of complex mixtures at low-flow conditions (10-100 nano-liters per minute) and seamlessly integrated with nanoelectrospray ionization and controlled, jointly with themass spectrometer, within the same software environment. In addition, the combined system must have; • Two atmospheric pressure ionisation interfaces; heated electrospray ionisation (HESI) and nano-spray ionisation (NSI). • A nanoflow UHPLC (ultra-high performance liquid chromatography) instrument that can be operated with the ultrahigh-resolution mass spectrometer, and the combined UHPLCHRMS system is operated within the same software environment. • A nanoflow UHPLC instrument capable of operating from 1 nanoliter per minute to 100 microliter per minute in flow rate, and at backpressures up to 1500 bar. • A nanoflow UHPLC instrument that consist of a binary high-pressure gradient pump, splitloop autosampler, an active nanoflow control unit and onboard user interface for immediate operation. • A UHPLC instrument capable of maintaining sample temperature control within 4-40 oC and holding at least 216 sample vials at the same time. • The UHPLC sampler must support a sample capacity of four sample racks and well plates (96 and 384, deep and shallow) without the need for external devices such as plate feeder. • The user interface must provide guided workflow exchange and maintenance procedures. • The mass spectrometer (MS) must be capable of operating at one million or higher in mass resolution at mass-to-charge (m/z) 200 to resolve complex environmental matrices. • A mass spectrometer capable of performing higher-energy collisional dissiciation and ultraviolet photodissociation for multi-stage MSn-fragmentation in liquid chromatography time scale. • A mass spectrometer capable of fragment ion detection in either ion trap or high-resolution analyzer • A mass spectrometer capable of isolating precursor ions with a quadrupole filter with 0.7 FWHM resolution for 50<m/z<1000. • A mass spectrometer that can perform automated iterative data-dependent acquisition in an integrated software solution. • A mass spectrometer that can perform data-dependent acquisition and data-independent acquisition. • A mass spectrometer with three mass analyzers build on quadrupole, linear ion trap, and Orbitrap technology. • A mass spectrometer with two independent mass detectors - one of them based linear ion trap technology - and both detectors must be capable of operating in parallel with each other. • A mass spectrometer with a removable ion sweep cone. • The mass spectrometer must be capable of switching polarities within 25 mili seconds • The mass spectrometer must be able to perform up to 10 stages of data-dependent fragmentations (MSn). • A mass spectrometer with normalized collision energy capability to automatically compensate for the mass dependent energy deposition and provide instrument-to-instrument fragmentation reproducibility. • A mass spectrometer with a data-dependent decision tree logic to automatic determine optimal fragmentation technique and analyzer during the LC run. • The high resolution mass analyzer must at least have an intra-spectrum dynamic range of 5000. • An ultraviolet photodissociation technology using a 213 nm laser architecture that is fully integrated in the mass spectrometer.

Internal identifier : 10694

5.1.1.

Purpose

Main nature of the contract : Supplies

Main classification ( cpv ): 38433100 Mass spectrometer

Additional classification ( cpv ): 38000000 Laboratory, optical and precision equipments (excl. glasses), 38400000 Instruments for checking physical characteristics, 38430000 Detection and analysis apparatus, 38433000 Spectrometers

5.1.2.

Place of performance

Postal address : Miljøvej, building 113

Town : Kgs. Lyngby

Postcode : 2800

Country subdivision (NUTS) : Københavns omegn ( DK012 )

Country : Denmark

5.1.3.

Estimated duration

Duration : 1 Year

5.1.6.

General information

Procurement Project not financed with EU Funds.

The procurement is covered by the Government Procurement Agreement (GPA) : yes

5.1.15.

Techniques

Framework agreement :

No framework agreement

Information about the dynamic purchasing system :

No dynamic purchase system

5.1.16.

Further information, mediation and review

Review organisation : Klagenævnet for Udbud

Information about review deadlines : Complaint regarding direct award of contract: Complaint that the Contracting Authority, contrary to the Public Procurement Act, has concluded a contract without prior publication of a contract notice in the European Union Official Journal must be submitted no later than 30 calendar days from the date after a contract award notice has been published by the Contracting Authority in the European Union Official Journal and that contract award notice includes the grounds for the decision to award the contract directly, cf. lov om Klagenævnet for Udbud (Complaints Board for Tenders) § 7, section 3.

Organisation providing additional information about the procurement procedure : Danmarks Tekniske Universitet - DTU

Organisation providing offline access to the procurement documents : Danmarks Tekniske Universitet - DTU

Organisation providing more information on the review procedures : Konkurrence- og Forbrugerstyrelsen

Organisation whose budget is used to pay for the contract : Danmarks Tekniske Universitet - DTU

Organisation executing the payment : Danmarks Tekniske Universitet - DTU

Organisation signing the contract : Danmarks Tekniske Universitet - DTU

Direct award :

Justification for direct award : The contract can be provided only by a particular economic operator because of an absence of competition for technical reasons

Other justification : As mentioned above DTU Sustain is working with environmental forensics and metabolomic investigations to study the fate and occurrence of chemicals and small molecules dispersed into the environment. The work involves creating untargeted metabolomic and non-target chemical analysis data recordings of trace level chemicals in complex environmental samples using liquid chromatography hyphenated with ultrahigh-resolution mass spectrometry. To be able to make these investigations, DTU wants to procure the instrument described above. The system will be essential for the research and teaching at DTU Sustain in describing and understanding environmental fate and occurrence processes of emerging pollutants. After extensive market research of commercially available systems and suppliers, DTU Sustain has concluded that the NanoUHPLC-HRMS/MS IQ-X system operating at 1 million in mass resolution with UVPD from Thermo Scientific is the only instrument meeting the high technical requirements needed for DTU Sustain to perform the variety of state-of-the-art experimental environmental research. Purchasing the NanoUHPLC-HRMS/MS IQ-X platform operating at 1 million in mass resolution with UVPD system from Thermo Scientific will fulfil the requirements from DTU Sustain and its broader user base and research areas as described above. No other supplier can deliver a similar system capable of solving the listed challenges.

6.1.

Result lot identifier : LOT-0000

6.1.2.

Information about winners

Winner :

Official name : Thermo Electron A/S

Tender :

Tender identifier : Thermo Electron A/S

Identifier of lot or group of lots : LOT-0000

Value of the tender : 4 500 000,00 DKK

The tender was ranked : no

Contract information :

Identifier of the contract : Thermo Electron A/S

Date on which the winner was chosen : 05/03/2026

Information about European Union funds :

Organisation signing the contract : Danmarks Tekniske Universitet - DTU

8.1.

ORG-0001

Official name : Danmarks Tekniske Universitet - DTU

Registration number : 30060946

Postal address : Anker Engelunds Vej 1

Town : Kgs. Lyngby

Postcode : 2800

Country subdivision (NUTS) : Københavns omegn ( DK012 )

Country : Denmark

Contact point : Katrine Freiesleben Petersen

Email : kafre@dtu.dk

Telephone : +45 45252525

Internet address : https://www.dtu.dk

Buyer profile : https://eu.eu-supply.com/ctm/company/companyinformation/index/165863

Roles of this organisation :

Buyer

Organisation providing additional information about the procurement procedure

Organisation providing offline access to the procurement documents

Organisation signing the contract

Organisation whose budget is used to pay for the contract

Organisation executing the payment

8.1.

ORG-0002

Official name : Klagenævnet for Udbud

Registration number : 37795526

Postal address : Nævnenes hus, Toldboden 2

Town : Viborg

Postcode : 8800

Country subdivision (NUTS) : Østjylland ( DK042 )

Country : Denmark

Email : klfu@erst.dk

Telephone : +45 35291000

Internet address : http://www.klfu.dk

Roles of this organisation :

Review organisation

8.1.

ORG-0003

Official name : Konkurrence- og Forbrugerstyrelsen

Registration number : 10294819

Postal address : Carl Jacobsens Vej 35

Town : Valby

Postcode : 2500

Country subdivision (NUTS) : Byen København ( DK011 )

Country : Denmark

Email : kfst@kfst.dk

Telephone : +45 41715000

Internet address : http://www.kfst.dk

Roles of this organisation :

Organisation providing more information on the review procedures

8.1.

ORG-0004

Official name : Thermo Electron A/S

Registration number : 28314388

Postal address : Gydevang 33

Town : Allerød

Postcode : 3450

Country subdivision (NUTS) : Nordsjælland ( DK013 )

Country : Denmark

Roles of this organisation :

Tenderer

Winner of these lots : LOT-0000

8.1.

ORG-0005

Official name : Mercell Holding ASA

Registration number : 980921565

Postal address : Askekroken 11

Town : Oslo

Postcode : 0277

Country subdivision (NUTS) : Oslo ( NO081 )

Country : Norway

Contact point : eSender

Email : publication@mercell.com

Telephone : +47 21018800

Fax : +47 21018801

Internet address : http://mercell.com/

Roles of this organisation :

TED eSender

Notice identifier/version : 182365cc-d3f8-4ff3-845d-bb9241cd807f - 01

Form type : Direct award preannouncement

Notice type : Voluntary ex-ante transparency notice

Notice subtype : 25

Notice dispatch date : 05/03/2026 09:22:52 (UTC+00:00) Western European Time, GMT

Notice dispatch date (eSender) : 05/03/2026 10:01:17 (UTC+00:00) Western European Time, GMT

Languages in which this notice is officially available : English

Notice publication number : 156946-2026

OJ S issue number : 46/2026

Publication date : 06/03/2026

Fakta om udbudet

Low-flow liquid chromatography ultrahigh-resolution mass spectrometry platform

Danmarks Tekniske Universitet - DTU