Internet address(es):

Main address: www.dtu.dk

Address of the buyer profile: www.dtu.dk

Fusion ID-X, Vanquish Duo, LC-MS)

Novo Nordisk Foundation Center for Biosustainability intends to purchase a High Resolution-Accurate Mass mass spectrometer (HRAM-MS) for analysis of complex samples for metabolomics and compound identification.

Denmarks Technical University

Novo Nordisk Foundation Center for Biosustainability intends to purchase a High Resolution-Accurate Mass mass spectrometer (HRAM-MS) for analysis of complex samples for metabolomics and compound identification. The MS instrument must besides high precision also be fast scanning, as the samples contains several thousands of compounds, and the analysis time need to be as short as possible. The MS must be capable of producing very detailed information on every single compound, which is of outmost importance for determining the chemical structure and thereby the identification of the analysed compound. The MS needs to be coupled to a binary HPLC system and all the parts must be controlled by the same software. To obtain the best coverage the instruments must have two independent mass analysers, which can be operated in parallel.

In metabolomics/compound identification, the ability to identify small molecules from their mass spectra is crucial. Very high mass resolution is required to limit the number of possible chemical formulas, and a minimum of 60 000 FWHM is required. The instrument requested has a resolution up to 500 000 FWHM. Furthermore, high-resolution fragmentation patterns are needed for structural elucidation.

The current instrument provides two modes of fragmentation — collision induced dissociation (CID) and higher-energy collisional dissociation (HCD) — and the ability to fragment multiple times (MSn), which is not available on any other high resolution MS. MSn significantly enhances structure elucidation, for example, in the analysis of lipids, where MS3 is usually required to identify the unsaturation locations on the acyl chain(s).

The system will be an extension of CfB’s existing platform for compound identification. With only a few qualified operators of this highly specialised equipment, it is important that the system is fully compatible with the existing systems, in order to reduce errors and enhance mastery. This further ensure that analytical methods can be moved between instruments without further development and optimisation.

CfB finds that the above-mentioned specifications only can be covered by the Fusion ID-X from Thermo Fisher Scientific.

Novo Nordisk Foundation Center for Biosustainability intends to purchase a High Resolution-Accurate Mass mass spectrometer (HRAM-MS) for analysis of complex samples for metabolomics and compound identification. The MS instrument must besides high precision also be fast scanning, as the samples contains several thousands of compounds, and the analysis time need to be as short as possible. The MS must be capable of producing very detailed information on every single compound, which is of outmost importance for determining the chemical structure and thereby the identification of the analysed compound. The MS needs to be coupled to a binary HPLC system and all the parts must be controlled by the same software. To obtain the best cover-age the instruments must have two independent mass analysers, which can be operated in parallel.

In metabolomics/compound identification, the ability to identify small molecules from their mass spectra is crucial. Very high mass resolution is required to limit the number of possible chemical formulas, and a minimum of 60,000 FWHM is required. The instrument requested has a resolution up to 500 000 FWHM. Furthermore, high-resolution fragmentation patterns are needed for structural elucidation.

The current instrument provides two modes of fragmentation - collision induced dissociation (CID) and higher-energy collisional dissociation (HCD) – and the ability to fragment multiple times (MSn), which is not available on any other high resolution MS. MSn significantly enhances structure eluci-dation, for example, in the analysis of lipids, where MS3 is usually required to identify the unsatura-tion locations on the acyl chain(s).

The system will be an extension of CfB’s existing platform for compound identification. With only a few qualified operators of this highly specialised equipment, it is important that the system is fully compatible with the existing systems, in order to reduce errors and enhance mastery. This further ensure that analytical methods can be moved between instruments without further development and optimisation.

CfB finds that the above-mentioned specifications only can be covered by the Fusion ID-X from Thermo Fisher Scientific.

Internet address: https://erhvervsstyrelsen.dk/klagenaevnet-for-udbud

Complaint regarding the award of contract:

Complaint regarding the award of contract must be submitted no later than 45 calendar days from the date after the Contracting Authority has published a contract award notice in the European Union Official Journal informing that the Contracting Authority has awarded the contract, cf. Law regarding Complaints board (in Danish Klagenævnet for Udbud) § 7, section 2, subsection 1.

Complaint regarding the award of a contract under a framework agreement with a reopening of the competition:

Complaint regarding the award of a contract under a framework agreement with a reopening of the competition shall be submitted no later than 30 calendar days form the date after the Contracting Authority has notified the concerned Tenderers that a contract has been awarded, if the notification includes the grounds for the decision, cf. Law regarding Complaints board (in Danish Klagenævnet for Udbud) § 7, section 2, subsection 2.

Complaint regarding the award of a framework agreement:

Complaint regarding the award of a framework agreement must be submitted no later than 6 months from the date after the Contracting Authority have notified the concerned Candidates and Tenderers that award of contract has happened, cf. Law regarding the Complaints board (in Danish Klagenævnet for Udbud) § 7, section 2, subsection 3.

Complaint regarding direct award of contract:

Complaint regarding the Contracting Authority’s award of contract without prior publication of a contract notice in the European Union Official Journal must be submitted no later than 30 calendar days from the date after a contract award notice has been published by the Contracting Authority in the European Union Official Journal and that contract award notice includes the grounds for the decision to award the contract directly, cf. Law regarding Complaints board (in Danish Klagenævnet for Udbud) § 7, section 3.

Compliant regarding public procurements below the EU threshold:

Complaint regarding public procurements below the EU threshold must be submitted no later than 45 calendar days from the date after the Contracting Authority has notified the Tenderers about the award of contract if this notification includes the grounds for the decision; and no later than 6 months after the date where the Contracting Authority has notified the Candidates and Tenderers about that award of a framework agreement, if the notification includes the grounds for the decision, cf. Law regarding Complaints board (in Danish Klagenævnet for Udbud) § 7, section 4, subsections 1 and 2. Compliant regarding a decision on shortlisting on procurement below the EU threshold must be submitted no later than 20 calendar days from the date after the Contracting Authority has sent a notification to the concerned Candidates regarding who has been selected and this notification includes the grounds for the decision, cf. Law regarding Complaints board (in Danish Klagenævnet for Udbud) § 7, section 5.