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2021/S 008-014080
Udbud med forhandling uden forudgående offentliggørelse


University of Copenhagen


Oxford Nanopore Technologies
Edmund Cartwright House 4 Robert Robinson Avenue
OX4 4GA Oxford

Acquisition of a Oxford Nanopore Promethion 24

University of Copenhagen

Voluntary ex ante transparency notice


Legal Basis:
Directive 2014/24/EU

Section I: Contracting authority/entity

I.1) Name and addresses
Official name: University of Copenhagen
Postal address: Nørregade 10
Town: Copenhagen K
NUTS code: DK01 Hovedstaden
Postal code: 1165
Country: Denmark
Contact person: Mahmut Yüksel
E-mail: FGN253@ku.dk
Internet address(es):
Main address: www.KU.dk
I.4) Type of the contracting authority
Body governed by public law
I.5) Main activity

Section II: Object

II.1) Scope of the procurement
II.1.1) Title:

Acquisition of a Oxford Nanopore Promethion 24

II.1.2) Main CPV code
38900000 Miscellaneous evaluation or testing instruments
II.1.3) Type of contract
II.1.4) Short description:

The Promethion will purchased from Oxford Nanopore Technologies (ONT), and involves a sequencing machine and regular shipments of chemistry kits used for sequencing. The unique machine is able to generate single molecule sequencing reads spanning hundreds of kilobases in real-time. The machine will be used by BRIC researchers to perform nucleic acid sequencing of biological material. The equipment will be placed in the sequencing core at BRIC.

II.1.6) Information about lots
This contract is divided into lots: no
II.1.7) Total value of the procurement (excluding VAT)
Value excluding VAT: 1 460 000.00 DKK
II.2) Description
II.2.3) Place of performance
NUTS code: DK01 Hovedstaden
II.2.4) Description of the procurement:

ONT was founded in 2005 to develop a disruptive, electronic, single molecule sensing system based on nanopore science. The company has a unique nanopore platform that uses ion current changes across the pore to identify nucleotide composition of long nucleic acid molecules.

II.2.5) Award criteria
II.2.11) Information about options
Options: no
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds: no
II.2.14) Additional information

Section IV: Procedure

IV.1) Description
IV.1.1) Type of procedure
Negotiated procedure without prior publication
  • The works, supplies or services can be provided only by a particular economic operator for the following reason:
    • protection of exclusive rights, including intellectual property rights

The ONT sequencing machine will be able to provide unprecedented resolution of genetic and epigenetic alterations in both patient-derived tissue and various biological models, ranging from bacteria and viruses to complex organisms, such as higher plants and mammals. Several important projects require the usage of ONT including:

Genome phasing and resolving complex SVs, mRNA isoforms, RNA degradation, RNA splicing isoforms in mouse models, RNA ribosome modifications, DNA methylation modifications.

Oxford Nanopore has a broad patent portfolio, through in-house development and licensing agreements with third parties. Oxford Nanopore has an intellectual property portfolio of more than 650 issued patents and patent applications, in over 200 patent families. These cover all aspects of nanopore sensing including fundamental patents for nanopore sensing, and patents relating to DNA-sequencing.

List of patents: https://patents.justia.com/assignee/oxford-nanopore-technologies-limited

The following themes are included in Oxford Nanopore's patent portfolio:

• DNA base identification using a biological nanopore;

• addition of adapters to nanopores for sensing;

• modified nanopores for sensing;

• use of molecular motors in combination with nanopores;

• localising polymerases to a surface, including pore-bound localisation;

• use of solid-state nanopores for detecting labelled ssDNA and dsDNA;

• use of solid-state devices to control movement of polymers;

• detection and positional measurement of probes on a DNA strand as the strand passes through a nanoscale detector;

• methods of fabricating solid-state nanopores including multi-layered devices;

• the use of functionalised solid-state nanopores for molecular characterisation, including graphene, tunnelling currents and nanotubes;

• time-based multiplexed nanopore measurements on a single chip, including the incorporation of 96 well plate;

• use of voltage to control DNA under feedback;

• measurement of DNA interacting with a limited volume, such as a polymerase on a surface;

• array chip for parallel sensing from multiple channels;

• sequencing by means of detection of products of enzymatic action on DNA/RNA using a nanopore;

• the use of multiple 'nodes' to analyse samples in a federated/clustered manner to reduce the time to result, and improve operating efficiencies;

• methods and algorithms for nanopore signal analysis;

• Nanopore arrays/nanopore array structures;

• Direct RNA sequencing;

• protein characterisation using nanopores;

• chip/array architecture;

• methods of sensitivity enhancement.

IV.1.3) Information about framework agreement
IV.1.8) Information about the Government Procurement Agreement (GPA)
The procurement is covered by the Government Procurement Agreement: yes
IV.2) Administrative information

Section V: Award of contract/concession

V.2) Award of contract/concession
V.2.1) Date of contract award decision:
V.2.2) Information about tenders
The contract has been awarded to a group of economic operators: no
V.2.3) Name and address of the contractor/concessionaire
Official name: Oxford Nanopore Technologies
Postal address: Edmund Cartwright House 4 Robert Robinson Avenue
Town: Oxford
Postal code: OX4 4GA
Country: United Kingdom
E-mail: Jakob.Oertvig@nanoporetech.com
Telephone: +44 8450347900
Internet address: www.nanoporetech.com
The contractor/concessionaire will be an SME: no
V.2.4) Information on value of the contract/lot/concession (excluding VAT)
Total value of the contract/lot/concession: 1 460 000.00 DKK
V.2.5) Information about subcontracting

Section VI: Complementary information

VI.3) Additional information:
VI.4) Procedures for review
VI.4.1) Review body
Official name: Danish Public Contracts Appeal Board
Postal address: Nævnenes hus, toldboden 2
Town: Viborg
Postal code: 8800
Country: Denmark
E-mail: NH@naevneneshus.dk
Telephone: +45 72405600
Internet address: www.KLFU.dk
VI.5) Date of dispatch of this notice:

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