Fakta om udbudet

2021/S 199-519169
Udbud med forhandling uden forudgående offentliggørelse


University of Copenhagen


Leica Microsystems A/S
Åkandevej 21
2700 Brønshøj

Acquisition of a microscope Leica Thunder Imager 3D Live Cell

University of Copenhagen

Voluntary ex ante transparency notice


Legal Basis:
Directive 2014/24/EU

Section I: Contracting authority/entity

I.1) Name and addresses
Official name: University of Copenhagen
Postal address: Nørregade 10
Town: Copenhagen K
NUTS code: DK01 Hovedstaden
Postal code: 1165
Country: Denmark
Contact person: Mahmut Yüksel
E-mail: FGN253@ku.dk
Internet address(es):
Main address: www.KU.dk
I.4) Type of the contracting authority
Body governed by public law
I.5) Main activity

Section II: Object

II.1) Scope of the procurement
II.1.1) Title:

Acquisition of a microscope Leica Thunder Imager 3D Live Cell

II.1.2) Main CPV code
38510000 Microscopes
II.1.3) Type of contract
II.1.4) Short description:

NNF CBMR – Novo Nordisk Foundation Center for Basic metabolic Research


II.1.6) Information about lots
This contract is divided into lots: no
II.1.7) Total value of the procurement (excluding VAT)
Value excluding VAT: 2 096 316.00 DKK
II.2) Description
II.2.3) Place of performance
NUTS code: DK01 Hovedstaden
Main site or place of performance:

NNF CBMR – Novo Nordisk Foundation Center for Basic metabolic Research


II.2.4) Description of the procurement:

THUNDER Imager 3D Live Cell is designed for imaging of cell culture assays. It allows a clear view of details, even deep within an intact sample, in real time without out-of-focus blur. This is achieved with a new opto-digital method, Computational Clearing, created by Leica. The THUNDER Imager minimizes photo-bleaching and provides high performance imaging and high throughput, which helps to maintain optimal physiological conditions and leads to better workflow efficiency and statistics.

II.2.5) Award criteria
II.2.11) Information about options
Options: no
II.2.13) Information about European Union funds
The procurement is related to a project and/or programme financed by European Union funds: yes
Identification of the project:

ERC grant agreement No. [101002725]

II.2.14) Additional information

Section IV: Procedure

IV.1) Description
IV.1.1) Type of procedure
Negotiated procedure without prior publication
  • The works, supplies or services can be provided only by a particular economic operator for the following reason:
    • absence of competition for technical reasons

To which purpose we will use the instrument:

We are studying and developing complex in vitro cell structures including primary adipocytes, IPS derived neurons, organoids, spheroids and 3D cultures. We will use these cell models to study response to candidate molecules derived from our omics screenings. In these cell models, we are setting up multiplex staining protocols. For candidates successful in vitro we will proceed with in vivo stimulation. We need an instrument with for live cell imaging, to access the development of our cell models, as well as fixed cell imaging for multiplex FISH analysis. We also need an instrument for tissue section imaging. To meet our requirements, we need a system that can provide optimal physiological conditions for our sensitive cell models collect complex data and at the same time produce publication-ready, high-resolution images. Finally, the instrument must be user friendly.

Which unique characteristics will be used:

We have identified “THUNDER Imager Live Cell & 3D Cell Culture & 3D Assay” (hereafter called THUNDER) as an instrument that successfully and uniquely meet all our requirements.

• THUNDER acquires large datasets of fluorescent images in numerous fluorescence channels of several Z planes in high speed with automated quantification (Patent DE102018128281B3).

• THUNDER feature the innovative Leica technology Computational Clearing (pending European patent: WO2019185174A1). It efficiently removes out-of-focus blur in real time, enabling imaging of 3D specimens with camera-based fluorescence microscopes. This technology is crucial for the type of samples we will use, which will have a wide range in thickness and complexity.

• THUNDER is user friendly with the option of both computational and manual adjustment of focus.

• THUNDER offers a Fluorescence Intensity Manager (FIM) option, which ensures low phototoxicity and photobleaching (Patent US 7,379,238).

• THUNDER comes with temperature control, humidity and gas concentrations with dedicated environmental control hardware and integrated software control.

• In order to accommodate the highest repeatability, THUNDER is equipped with a closed loop focus, which allow multi-point time-lapse experiments with 20nm repositioning accuracy.

IV.1.3) Information about framework agreement
IV.1.8) Information about the Government Procurement Agreement (GPA)
The procurement is covered by the Government Procurement Agreement: yes
IV.2) Administrative information

Section V: Award of contract/concession

V.2) Award of contract/concession
V.2.1) Date of contract award decision:
V.2.2) Information about tenders
The contract has been awarded to a group of economic operators: no
V.2.3) Name and address of the contractor/concessionaire
Official name: Leica Microsystems A/S
Postal address: Åkandevej 21
Town: Brønshøj
NUTS code: DK Danmark
Postal code: 2700
Country: Denmark
E-mail: dkinfo@leica-microsystems.com
Telephone: +45 44540101
Internet address: www.leica-microsystems.com
The contractor/concessionaire will be an SME: no
V.2.4) Information on value of the contract/lot/concession (excluding VAT)
Total value of the contract/lot/concession: 2 096 316.00 DKK
V.2.5) Information about subcontracting

Section VI: Complementary information

VI.3) Additional information:
VI.4) Procedures for review
VI.4.1) Review body
Official name: Danish Public Contracts Appeal Board
Postal address: Nævnenes hus, toldboden 2
Town: Viborg
Postal code: 8800
Country: Denmark
E-mail: NH@naevneneshus.dk
Telephone: +45 72405600
Internet address: www.KLFU.dk
VI.5) Date of dispatch of this notice:

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